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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T68523 | AMG-628, (S)- | ||
AMG-628, (S)-, is the S isomer of AMG-628 --- a potent, ATP-competitive inhibitor of Raf kinases. AMG-628 displays selectivity for Raf kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1... | |||
T29973 | AMG-628 | AMG628,AMG 628,CHEMBL226574,UNII-28J966TN3X | |
AMG-628 is an effective and ATP-competitive RAF kinase inhibitor. AMG-628 has been shown to inhibit growth and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with B-RAFV600E mutations. |